Early Growth in Offspring of Diabetic Mothers
نویسندگان
چکیده
منابع مشابه
Early growth in offspring of diabetic mothers.
OBJECTIVE By age 5 years, offspring of diabetic mothers (ODMs) are heavier and have altered glucose metabolism compared with offspring of mothers without diabetes (non-DMs). This study evaluates the growth pattern of ODMs before the age of 5 years. RESEARCH DESIGN AND METHODS Anthropometric measures (z scores) from birth, 1.5 years, and 7.7 years in Pima Indian children were compared by mater...
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Maternal diabetes induces fetal alterations, resulting in lasting consequences for the glucose tolerance of the offspring over several generations. In our experimental rat model, circulating prolactin, oestradiol, progesterone and corticosterone levels, known to influence insulin secretion and action, are determined in plasma of female adult offspring of mildly and severely diabetic mothers. Pr...
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Studies were conducted in rats to determine the effect of maternal diabetes and the consequent hyperglycemia on cardiovascular function in the offspring. Diabetes was induced in pregnant Wistar rats through streptozotocin injection (50 mg/kg). Cardiovascular parameters were measured in 2-mo-old offspring animals of diabetic (OD, n=12) and control rats (OC, n=8). Arterial pressure (AP), heart ra...
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Recent epidemiological studies in people whose birth weights were recorded many years ago suggest links between impaired growth during early life and the development of diseases, including diabetes, much later in life. The long-term effects of retarded early growth are proposed to result from malnutrition at critical periods of fetal or infant development leading to reduction in the growth of o...
متن کاملOffspring of Chronic Alcoholic Mothers
same observers (K. J. and D. W. S.). Four of these children were recognised as having a similar pattern of altered growth and morphogenesis. Thereafter, two other children were ascertained by the abnormal features identified in the first four patients, while the remaining two affected children were ascertained because their mothers were chronically alcoholic. The mothers of the affected patient...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2005
ISSN: 0149-5992,1935-5548
DOI: 10.2337/diacare.28.3.585